Acetylcholine receptor channel ionic selectivity: ions experience an aqueous environment.

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Acetylcholine receptor channel ionic selectivity: ions experience an aqueous environment.

Alkali metal and alkaline earth cations pass readily through the acetylcholine receptor channel. Monovalent cations with larger crystal radii are more permeant than ones with smaller radii. For divalent ions, this selectivity sequence is reversed: smaller ions are more permeant than larger ones. This reversal in selectivity sequence with change of valence from 1 to 2 can be naturally accounted ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1983

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.80.19.6110